Malaria var Gene Expression: Keeping Up with the Neighbors

SnapShot: var Gene Expression in the Malaria Parasite

Differential var gene expression in children with malaria and antidromic effects on host gene expression.

Among 62 children with mild malaria, cerebral malaria, or severe malarial anemia, we analyzed the transcription of different var gene types. There was no difference in parasitemia level or body temperature between groups. However, a significantly different expression pattern was observed in children with cerebral malaria, compared with that in patients in the other 2 groups: children with cereb...

Keeping Up With the Clock

Estimates of obesity prevalence based on the 2013 to 2014 National Health and Nutrition Examination Survey average almost 40%, corresponding to a 7% increase from the 1999 to 2000 cycle. Similar alarming trajectories are reported worldwide, along with increasing concerns for related health risks. The traditional concept that obesity results from a mere imbalance between energy intake and energy...

Keeping Up with the Standards

There has been a not-so-silent revolution in research over the last decade. Though researchers had been publishing guidelines and decrying the disarray or lack of uniform design standards for some time, evidence-based guidelines to help direct research design and publication are relatively new. The first major undertaking was CONSORT (Consolidated Standards of Reporting Trials), published in 19...

Keeping up with the Joneses

In field-capital theory, people acquire economic, social and cultural capital which they deploy in social arenas known as "fields" to compete for positions of distinction and status. Competitive behaviour in these fields is of interest to marketers. Examining human behaviour through the lens of field and capital theory highlights the importance of the competition motive in explaining consumers'...